The effect of local insulin injection on the wound healing process

The effect of local insulin injection on the healing process of split-thickness skin graft donor site in comparison to the placebo

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20111118008122N2

Enrollment

Registered

2019-06-24

Start date

2019-06-10

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin Grafting. Complications of skin graft (allograft) (autograft)

Interventions

Intervention 1: In the case group, a single dose of NPH insulin (Exir, Iran) with the concentration of 1IU/ml and the dose of 2 ccs will be injected subdermally at 12 points of the wound. After the in

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: STSG donor site at least more than 10 cm length and age between 18 and 65 year-old

Exclusion criteria

Exclusion criteria: Age below 18 years Age above 65 years Diabetes Malnutrition History of vascular diseases Smoking Pregnancy

Design outcomes

Primary

Measure	Time frame
Evaluating epithelized area for assessing the wound site. Timepoint: ?At day 7, 14 and 21 after STSG. Method of measurement: ImageJ software.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSohrab Moradi Bajestani

Tehran University of Medical Sciences

dr.smoradib@gmail.com+98 912 377 0755

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026