Spinal anesthesia. Other complications of spinal and epidural anaesthesia during pregnancy
Conditions
Interventions
Intervention 1: Case group: 4 mg (2cc) ondansetron IV inject Slowly before spinal anesthesia. Intervention 2: Control group: 2cc sterile water IV injection before spinal anesthesia.
Prevention
Placebo
Case group: 4 mg (2cc) ondansetron IV inject Slowly before spinal anesthesia.
Control group: 2cc sterile water IV injection before spinal anesthesia.
Sponsors
Research vice Chancellorship, Hamedan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: pregnant healthy women who are candidate for elective cesarean section with spinal anesthesia. Exclusion criteria: motion sickness; hypertension; weight greater than 100kg; hepatic disease; migraine; allergy to ondansetron group drugs, using drugs that effect blood pressure or heart rate or serotonin receptor.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bradycardia. Timepoint: Every 3 min till 10 min after anesthesia then every 5 min. Method of measurement: Heart rate per minute, automatic monitoring.;Hypotension. Timepoint: Every 3min till 10min after anesthesia, then every 5min till minute 30. Method of measurement: mmHg, automatic. | — |
Secondary
| Measure | Time frame |
|---|---|
| Itching. Timepoint: Every 10 minute after anesthesia till minute 30. Method of measurement: Question from patient, scoring: 0 no- 1 mild- 2 severe (need to treat).;Nausea and vomiting. Timepoint: Every 10 minute after anesthesia till minute 30. Method of measurement: Question from patient, scoring: 0 no- 1 yes.;Mean consumed ephedrine. Timepoint: After anesthesia until end of operation. Method of measurement: Milligram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Bita Malekianzadeh
Hamedan University of Medical Sciences
Outcome results
None listed