ketamine effect for pain releaf after abdominal surgery

Effect of adding ketamine to fentanyl patient-controlled analgesia for postoperative pain after laparotomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111128075N1

Enrollment

100

Registered

2012-03-27

Start date

2012-04-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: cholelihtiasis. Condition 2: noneinflamatory disorders of ovary. Calculus of gallbladder with acute cholecystitis Follicular cyst of ovary

Interventions

Intervention 1: In group 1 the IV PCA Pump will be filled with 0.01 mg/ml fentanyl and 0.5 mg/ml ketamine. Intervention 2: In group 2 only 0.01 mg/ml fentanyl will be used in pumps.

Treatment - Drugs

In group 1 the IV PCA Pump will be filled with 0.01 mg/ml fentanyl and 0.5 mg/ml ketamine.

In group 2 only 0.01 mg/ml fentanyl will be used in pumps.

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: 100 Patients age between 20- 60 years, who candidate for abdominal surgery, ASA physical status class I & II, Exclusion criteria: 1 - Substance and alcohol abuse 2 - Chronic pain or daily intake housing 3 - Those who do not cooperate 4 - A history of seizures 5 - Liver dysfunction or abnormal liver enzymes 6 - Sensitivity to drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Every 6 hours until 48 hours after surgery. Method of measurement: VAS (visual analogous scale).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Minow Sedaghat

Hazrateh Rasul Akram Hospital, Tehran University of Medical Sciences

m-sedaghat@razi.tums.ac.ir; sedaghat1357@gmail.com+98 21 6435 2326

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026