Clinical evaluation of different topical formulations of Fumaria officinalis extract on the Vitiligo and analysis of its Fumaric acid content by HPLC.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111108022N1

Enrollment

Registered

2011-12-08

Start date

2011-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo. disorders of pigmentation

Interventions

Intervention 1: Intervention lesion: topical formulation of hydroalcoholic extract from fumaria officinalis in three different percents for one symmetric section of the patches, three times a day, and

Treatment - Drugs

Intervention lesion: topical formulation of hydroalcoholic extract from fumaria officinalis in three different percents for one symmetric section of the patches, three times a day, and follow up every

Control lesion: use the none of topical treatments on the other side of the symmetric section of patches.

Eligibility

Sex/Gender

All

Age

15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: lasting more than 6 month after diagnosis, age 11-60, filling informed consent. Exclusion criterion: Pregnancy, Lactation, not filling consent form.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Repigmentation rate after treatment. Timepoint: Every 2weeks during 4 months. Method of measurement: Observtion.	—

Secondary

Measure	Time frame
Diameter reduction. Timepoint: every 2 weeks during 4 months. Method of measurement: Evaluation of diameter with precise measurement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr GholamReza Bahrami

Kermanshah University of Medical Sciences

gbahrami@kums.ac.ir+98 83 1428 1562

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026