clinical trial of effect of Silybum marianum extract capsules on systemic lupus erythematosus patients

Double-blinde placebo-controlled clinical trial of effect of Silybum marianum extract capsules on systemic lupus erythematosus patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20111105008013N9

Enrollment

Registered

2020-07-12

Start date

2020-07-12

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic Lupus Erythematosus. Systemic lupus erythematosus (SLE)

Interventions

Intervention 1: Intervention group: Tab Prednisolone 5 mg/day, tab Methotrexate 2.5 mg/day and tabAzathioprine 50 mg/day (main treatment) with 140 mg Milk thistle capsules 3 times a day for one month

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: age 18-50 having active lupus

Exclusion criteria

Exclusion criteria: diabetes cardiovascular diseases using irrelevant drugs with lupus pregnancy lactation

Design outcomes

Primary

Measure	Time frame
Score of Quality of life questionnaire. Timepoint: At the intervention begining and one month later. Method of measurement: Lupus QOL questionnaire.;Score of Systemic Lupus Erythematosus Activity questionnaire. Timepoint: At the intervention begining and one month later. Method of measurement: SLA questionnaire.	—

Secondary

Measure	Time frame
Side effects. Timepoint: One month after the intervention beginning. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Siahpoosh

Ahvaz University of Medical Sciences

Amirsiahpoosh@yahoo.com+98 61 3334 2197

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026