Comparison of the effects of "EECP Combined with Cardiac Rehabilitation" and "only Cardiac Rehabilitation" on the treatment of ischemic heart disease

Effects of "Enhanced External Counterpulsation Combined with Cardiac Rehabilitation" and "only Cardiac Rehabilitation" on Clinical Parameters and plasma Nitic oxide, Endoteline and High sensitive CRP in the Patients with Coronar artery Diseases

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111024422N3

Enrollment

Registered

2011-11-21

Start date

2011-11-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic heart disease. Ischemic heart disease

Interventions

Intervention 1: Group A: only 20-sessions cardiac rehabilitation, based on CR-2 protocol includes a 10 minutes warm up, 20 minutes walking on treadmill ,cycling on stationary bike, and finally 5 minu

Rehabilitation

Group A: only 20-sessions cardiac rehabilitation, based on CR-2 protocol includes a 10 minutes warm up, 20 minutes walking on treadmill ,cycling on stationary bike, and finally 5 minutes of relaxatio

Group B: cardiac rehabilitation combined with 35 sessions of EECP that each session lasting one hour

Eligibility

Sex/Gender

All

Age

30 Years to 149 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients after myocardial infarction, age over 30 years old, ischemic heart disease which is documented by at least one of the followings: angiography, Perfusion scan, ECG, exercise Test, EF=30 Exclusion criteria: Arrhythmias that will lead to impaired performance, susceptibility to bleeding, Active thrombophlebitis, proven aortic aneurysms that require to surgery, pregnancy, patients with significant valvular heart disease (Severe AI-severe AS - severe MS), using of nitrocantine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Level of blood hsCRP. Timepoint: before beginning and at the end of study for all patients,also for group B befor EECP. Method of measurement: using the kit of hsCRP(mg/lit).;Level of blood Nitric oxide. Timepoint: before beginning and at the end of study for all patients,also for group B befor EECP. Method of measurement: using the kit of Nitric oxide (umol/lit).;Level of blood Endotelin-1. Timepoint: before beginning and at the end of study for all patients ,also for group B before EECP. Method of measurement: using the kit of Endotelin-1( pg/lit).	—

Measure

Time frame

Level of blood hsCRP. Timepoint: before beginning and at the end of study for all patients,also for group B befor EECP. Method of measurement: using the kit of hsCRP(mg/lit).;Level of blood Nitric oxide. Timepoint: before beginning and at the end of study for all patients,also for group B befor EECP. Method of measurement: using the kit of Nitric oxide (umol/lit).;Level of blood Endotelin-1. Timepoint: before beginning and at the end of study for all patients ,also for group B before EECP. Method of measurement: using the kit of Endotelin-1( pg/lit).

—

Secondary

Measure	Time frame
Clinical parameters. Timepoint: before beginning and at the end of study for all patients. Method of measurement: quality of life questionnaire sf36, Canadian Cardiovascular Society Angina scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Seyyed Kazem Shakouri

Tabriz University of Medical Sciences

shakourik@tbzmed.ac.ir,zrazavia@gmail.com+98 41 1336 4672

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026