Evaluation of efficacy of gel prepared from plants of Quercus Brantii L and Coriandrum Sativum L on periodontal clinical indices.

Evaluation of efficacy of topical subgingival application of gel prepared from plants of Quercus Brantii L and Coriandrum Sativum L compared with placebo gel on periodontal clinical indices in moderate chronic periodontitis patients.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201111014877N7

Enrollment

Registered

2012-08-22

Start date

2012-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic pericoronitis Periodontitis:•NOS•complex•simplex

Interventions

Intervention 1: Ten patients were selected with moderate chronic periodontitis (with 4 or more sites with a probing depth of 3-5 mm). Totally seventy sites (pockets) were selected and divided into exp

Treatment - Drugs

Placebo

Ten patients were selected with moderate chronic periodontitis (with 4 or more sites with a probing depth of 3-5 mm). Totally seventy sites (pockets) were selected and divided into experimental and co

Control sites were treated with SRP and topical application of placebo gel into periodontal pockets. It was applied subgingivally using similar syringe and needle as that of experimental gel.

Eligibility

Sex/Gender

All

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: any systemic disease, any antibiotic therapy in last 1 month, no history of any periodontal therapy 3 months prior to the initial examination and any orthodontic therapy. Exclusion criteria: smoking habit, pregnancy, sites with severe caries and restoration, allergy to gel and other drugs used in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pocket depth. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Clinical attachment loss. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Papilla bleeding index. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Plaque index. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.	—

Measure

Time frame

Pocket depth. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Clinical attachment loss. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Papilla bleeding index. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.;Plaque index. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: With probe.

—

Secondary

Measure	Time frame
Tooth sensitivity. Timepoint: Before treatment, 1 and 3 months after treatment. Method of measurement: Visual examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Jaber Yaghini

Dental Faculty of Isfahan Medical University

j_yaghini@dnt.mui.ac.ir+98 31 1434 2136

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026