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Efficacy of Glucosamine in knee osteoarthrosis

Study the efficacy of Glucosamine phonophoresis in knee osteoarthrosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201111014203N2
Enrollment
36
Registered
2011-11-22
Start date
2011-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthrosis. Erosive (osteo)arthrosis

Interventions

Intervention 1: Intervention (3, Phonophoresis of glucosamine): Standard treatment (includes: IR, TENS and Exercise) with phonophoresis of glucosamine. Standard treatment includes: IR lasting for 20
Treatment - Other
Intervention (3, Phonophoresis of glucosamine): Standard treatment (includes: IR, TENS and Exercise) with phonophoresis of glucosamine. Standard treatment includes: IR lasting for 20 minutes in dista
Intervention (2, Ultrasound): Standard treatment (includes: IR, TENS and Exercise) with US. Standard treatment includes : IR lasting for 20 minutes in distance of 40-50 cm from knees, TENS in form of
Intervention (1, Placebo US): Standard treatment (includes: IR, TENS and Exercise) with placebo US. Standard treatment includes: IR lasting for 20 minutes in distance of 40-50 cm from knees, TENS in f

Sponsors

Deputy of Research, Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: presence of mechanical knee pain, osteophytes in knee X-ray, age above 50 years, morning stiffness lasting less than 30 minutes, crepitus in palpation of knee joint. Exclusion criteria: presence of other knee joint diseases, osteoarthrosis of hip and/or ankle joints, radicular pain originating from lumbar spine, physiotherapy history with intra/peri articular injection (corticosteroids or hyaluronic acid) during past six months, physiotherapy history during past six months, surgery history of knee joints, psychotic or mental disorders, neoplasm, infections, bleeding, neurologic disorders (sensory or motor)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Quality of Life. Timepoint: Before treatment and after 10 treatment sessions . Method of measurement: WOMAC INDEX Questionaire.;Duration of Morning stifness. Timepoint: Before treatment and after 10 treatment sessions . Method of measurement: Based on scale of 0-4.;Measurement of resting and activity pain. Timepoint: Before treatment and after 10 treatment sessions . Method of measurement: Based on Visual Analogue Scale (0-10).;Active range of motion of knee flexion. Timepoint: Before treatment and after 10 treatment sessions . Method of measurement: Based on Goniometery.;Swelling of knee joint. Timepoint: Before treatment and after 10 treatment sessions . Method of measurement: Based on tape measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Atefeh Aminian Far

Semnan University of Medical Sciences

aminfar83@yahoo.com aminianfar@razi.tums.ac.ir+98 23 1335 4182

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026