diabetes. Endocrine, nutritional and metabolic diseases
Conditions
Interventions
Intervention 1: Intervention group1: Inulin powder 10 g (2*5 gr)/d, divided into 2 portions of 5g each to be eaten during breakfast and dinner, for two months. Intervention 2: Placebo group: dextrin m
Treatment - Other
Treatment - Drugs
Intervention group1: Inulin powder 10 g (2*5 gr)/d, divided into 2 portions of 5g each to be eaten during breakfast and dinner, for two months
Intervention group2: Oligofructose-enriched inulin powder 10 g (2*5 gr)/d, divided into 2 portions of 5g each to be eaten during breakfast and dinner, for two months
Sponsors
Health and Nutrition Faculty, Tabriz University of Medical sciences
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 30-65 years old, 25= BMI <35, having diabetes at least 6 months prior to the study, consumption of blood glucose lowering drug,. typical ?ber intake <25 g ?ber/d and inulin fructans intake =200 g ?ber/d. Exclusion criteria: consumption of antioxidants supplements during last 3 months prior to the study, using insulin, pregnancy, lactation, acute renal disease
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dietary intake. Timepoint: 8 weeks. Method of measurement: 24 hours-food recal questionnaire.;Serum antioxidant status. Timepoint: 8 weeks. Method of measurement: measurement of SOD,GPX-H,TAC,MDA.;Total grelin level. Timepoint: 8 weeks. Method of measurement: Serum level of fasting total grelin.;Lipid profiles. Timepoint: 8 weeks. Method of measurement: TC, TG, LDL, HDL.;Insulin level. Timepoint: 8 weeks. Method of measurement: Serum level of fasting insulin.;Blood glucose & HbA1c. Timepoint: 8 weeks. Method of measurement: fasting blood glucose & HbA1c.;Inflammatory factors. Timepoint: 8 weeks. Method of measurement: HS-CRP,TNF-a,IL-6,IFN-?.;Anti-Inflammatory factor. Timepoint: 8 weeks. Method of measurement: IL-10. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropomethric indices. Timepoint: 8 weeks. Method of measurement: Weight, Height, BMI.WB,WHR.;Appetite. Timepoint: 8 weeks. Method of measurement: questionnaire.;Lipopolysaccharide. Timepoint: 8 weeks. Method of measurement: serum Lipopolysaccharide.;Blood pressure. Timepoint: 8 weeks. Method of measurement: blood pressure. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParvin Dehghan
Faculty of Health and Nutrition, Tabriz University Of Medical Sciences
Outcome results
None listed