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The effects of pure mastic gums, mastic gums enriched with probiotics and mastic gums with xylitol on cariogenic microflora and PH of saliva

The effects of pure mastic gums, mastic gums enriched with probiotics and mastic gums with xylitol on the number of Mutans streptococci, Lactobacilli and PH of saliva

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201110267910N1
Enrollment
42
Registered
2012-01-15
Start date
2012-01-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Caries. Other and unspecified infectious diseases

Interventions

Intervention 1: chewing xylitol containing mastic gum, three times a day after meal, 5 minutes each time. Intervention 2: chewing pure mastic gum, three times a day after meal, 5 minutes each time. In
Prevention
chewing probiotic enriched mastic gum, three times a day after meal, 5 minutes each time
chewing xylitol containing mastic gum, three times a day after meal, 5 minutes each time
chewing pure mastic gum, three times a day after meal, 5 minutes each time

Sponsors

Vice chancellor for research, Shahid Beheshti Dental School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Including criteria: 1) Dental students with the mean age of 25 years old; 2) Teeth brushing twice a day using fluoridated toothpaste. Excluding criteria: 1) history of systemic disease; 2) habitual use of xylitol or probiotic containing products; 3) previous use of systemic antibiotics and fluoride products at least four weeks before starting the study; 4) Existence of untreated carious teeth, gingivitis and periodontal diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Lactobacilli count of saliva. Timepoint: before and three weeks after intervention. Method of measurement: colony count(cfu).;PH of saliva. Timepoint: before and three weeks after intervention. Method of measurement: numerical value according to the reading of PH meter.;Mutans Streptococci count of saliva. Timepoint: before and three weeks after intervention. Method of measurement: colony count(cfu).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mina Biria

Shahid Beheshti Dental School

dr.biriam@dent.sbmu.ac.ir , dr.biriam@gmail.com+98 21 2990 2304

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026