Chronic Fatigue Syndrome. Postviral fatigue syndrome, Myalgic encephalomyelitis
Conditions
Interventions
Intervention 1: Intervention group: creatine supplement (produced by Karen company) is consumed for one month in the form of 25 grams in 5 divided doses in the first 5 days and then in the amount of 5
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18-65 years Meet US National Academy Of Medicine criteria (NAM), (have cognitive and/or orthostatic symptoms along with three of the following: A) substantial decrease or impairment in ability to participate in pre-illness levels of occupational, educational, social, or personal activities that has persisted for 6 months or more and is accompanied by profound fatigue, has a new onset (not lifelong), is not the result of ongoing excessive exertion, and is not significantly relieved by rest ???B) Post-exertional malaise (PEM) C) Sleep that is not restorative. Must have moderate to severe fatigue.
Exclusion criteria
Exclusion criteria: Currently have respiratory failure due to uncontrolled cardiopulmonary disease or COVID-19. Existence of acute infectious symptoms such as fever and vital sign abnormalities. Existence of severe musculoskeletal symptoms or other diseases that interfere with exercise. Existence history of severe allergies, neurological, rheumatological, or psychological disorders that significantly impact fatigue. Existence history of kidney disease, proteinuria, or abnormal kidney function tests such as elevated BUN and creatinine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue severity in Chalder's questionnaire. Timepoint: Before starting the intervention, ending the intervention. Method of measurement: Chalder's questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Function, Quality of Life. Timepoint: Before starting the intervention, ending the intervention. Method of measurement: GPAQ questionnaire, SF-36 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Alizadeh
Tehran University of Medical Sciences
Outcome results
None listed