Polycystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: The intervention group with clonidine tablets: In this intervention study, 100 women with polycystic ovary syndrome will take 0.2 mg of clonidine (a hypertension drug) daily for two mo
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Age 20 to 40 years (of reproductive age) Diagnosis of polycystic ovary syndrome based on the Rotterdam criteria Diagnosis of infertility (at least one year of unsuccessful attempts without using contraception) Having primary infertility The husband have not male infertility
Exclusion criteria
Exclusion criteria: There should be no female reproductive problems of the uterine system, fallopian tubes, etc., as diagnosed by a gynecologist Not having endocrine problems such as thyroid Absence of hormonal disorders (especially in the hypothalamic-pituitary-adrenal axis) Absence of chronic diseases such as illness, kidney failure, disorders of the digestive system organs, etc., as confirmed by a clinician Not taking medications such as injectable insulin No smoking, alcohol, drugs, psychotropic medications Not taking antidepressants Not being obese (BMI less than 27)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy rate. Timepoint: 2 to 5 pregnancy tests. Method of measurement: Baby check and, if pregnancy is suspected, a blood test to measure beta. | — |
Secondary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: Before and after the questionnaire. Method of measurement: Spielberger State-Trait Anxiety questionnaire & Beck anxiety questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarideh Zafari Zangeneh
Tehran University of Medical Sciences
Outcome results
None listed