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The effect of ondansetron and dexamethasone on reduction of post operative nausea and vomiting (PONV) in laparoscopic cholecystectomy

The effect of ondansetron and dexamethasone on reduction of post operative nausea and vomiting (PONV) in laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201110194093N2
Enrollment
90
Registered
2011-11-15
Start date
2011-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting after laparoscopic cholecystectomy. Vomiting following gastrointestinal surgery

Interventions

Intervention 1: Dexamethasone (8 mg, increased volume to 2 ml) before induction of anesthesia. Intervention 2: Ondansetron(4mg, increased volume to 2 ml) before induction of anesthesia. Intervention 3
Prevention
Dexamethasone (8 mg, increased volume to 2 ml) before induction of anesthesia

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Candidate for laparoscopic cholecystectomy, ASA class I-II, age 15-80 years Exclusion criteria: Gastroesophageal reflux - Severe obesity - difficult airway

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea after surgery. Timepoint: In the recovery room after surgery-6 and 24 hours after surgery. Method of measurement: Observation and history taking of patients, relatives and nursing staff.;Vomiting after surgery. Timepoint: In the recovery room after surgery-6 and 24 hours after surgery. Method of measurement: Observation and history taking of patients, relatives and nursing staff.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasood Entezariasl

Ardabil University of Medical Sciences

m.entezari@arums.ac.ir+98 45 1225 1688

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026