Skip to content

lidocaine cyclodextrin ophthalmic drop, a new choice in ophthalmic topical anesthesia

Study of the efficacy of lidocaine drop with cyclodextrin base in anesthesia for ophthalmic surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201110187829N1
Enrollment
100
Registered
2011-11-21
Start date
2011-11-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Pterygium. Condition 2: Symblepharon. Pterygium Conjunctival scars

Interventions

Intervention 1: study group: lidocaine-cyclodextrin 1% ophthalmic drop, 5 drops and 10 min before the intervention (pterygium, symblepharon, dysport injection, forced duction test). Intervention 2: co
Treatment - Drugs
study group: lidocaine-cyclodextrin 1% ophthalmic drop, 5 drops and 10 min before the intervention (pterygium, symblepharon, dysport injection, forced duction test)
control group: tetracaine hydrochloride ophthalmic drop, 5 drops and 10 min before the intervention (pterygium, symblepharon, dysport injection, forced duction test)

Sponsors

Vice chancellor of research, Mashhad university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients who are candidate to limited ocular inventions; aged from 15 to 65 years; cooperative psychologically for topical anesthesia Exclusion criteria: another corneal pathology at the same time that make the surgery difficult; positive alergic history to anesthetics; aged beneath 15 or above 65 years

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Patients' pain during the intervention. Timepoint: at the time of intervention to 5 min after it. Method of measurement: 0 to 10 visual analogue scale.;Patients' satisfaction. Timepoint: at the time of intervention to 5 min after it. Method of measurement: 0 to 4 designed scale.;Surgeon satisfaction. Timepoint: at the time of intervention to 5 min after it. Method of measurement: 0 to 4 designed scale.

Secondary

MeasureTime frame
Start and finish time of efficient anesthesia. Timepoint: 1, 5, 10 and 20 min after first drop. Method of measurement: conjuctival pinching.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHami Ashraf

Mashhad university of medical sciences

ashrafh821@mums.ac.irmrhami_ashraf@yahoo.com+98 51 1842 4685

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026