Infantile Hemangioma.
Conditions
Interventions
Intervention 1: Perform PDL laser(3 sessinns)with 4 weeks interval +daily application of topical propranolol by the patient up to 3 months. Intervention 2: PDL laser alone is performed (3 sessions wit
Treatment - Drugs
Treatment - Other
Perform PDL laser(3 sessinns)with 4 weeks interval +daily application of topical propranolol by the patient up to 3 months.
PDL laser alone is performed (3 sessions with 4 weeks interval)
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 2 Years
Inclusion criteria
Inclusion criteria: Inclusion crateria : 1-Hemangioma located in non-sensitive area(include nose-ear-eyelid-lips) 2-Patient compliance with study 3-No previous treatment(with systemic corticosteroids or other drugs) received in the last 3 months. 4-Patients shold not have any systemic involvement(congenital heart disease-renal disease) 5-Hemangioma in the proliferative phase of evolution(age<2 years). Exclusion crateria: 1-no response after 4 weeks of treatment 2-Allergic reaction to anyone of topical drugs. 3-Side effects of topical propranolol (e.g erythema,pruritus,inflamation......)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of topical propranolol with PDL laser and PDL laser alone in treatment of infantile hemangioma. Timepoint: 0-4-8-12-16 weeks. Method of measurement: Evaluation and comparision of lesion photographs according to VAS(Visual Analogue Scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of overall health of patient. Timepoint: 4-8-12-16 weeks after initial treatment. Method of measurement: Patients parents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mona Abdolreza
Razi Hospital
Outcome results
None listed