The effect of oral grape seed oil consumption on overweight and obese women

The effect of oral grape seed oil consumption on inflammatory factors and insulin resistance in over weight and obese women

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201110123320N2

Enrollment

Registered

2011-12-10

Start date

2011-11-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

over weight and obesity. Obesity due to excess calories

Interventions

Intervention 1: Grape seed oil consumption up to 15% of daily calorie instead of sunflower oil for two months in intervention group. Intervention 2: Continue to consumption of sunflower oil up to 15%

Prevention

Grape seed oil consumption up to 15% of daily calorie instead of sunflower oil for two months in intervention group

Continue to consumption of sunflower oil up to 15% of daily calorie for two months in placebo group

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- BMI equal or greater than 27; 2- following no weight loss or any special diet; 3-women with 20 until 50 years old. Exclusion criteria: 1- vitamin-mineral supplement consumption; 2- anti-inflammatory drugs consumption; 3- pregnancy or lactation; 4- being type 1 or 2 diabetes; 5-smoking; 6-recent illnesses; 7- recent surgery; 8- injuries.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Inflammatory factors. Timepoint: Beginning and end of the intervention. Method of measurement: TNF-a and hs-CRP measurement with special kits.;Insulin level. Timepoint: Beginning and end of the intervention. Method of measurement: measurement with special kits.;Fasting blood glucose level. Timepoint: Beginning and end of the intervention. Method of measurement: enzymatic method.	—

Secondary

Measure	Time frame
Anthropometry. Timepoint: beginning, second, fourth, sixth and end of the intervention. Method of measurement: Waist circumference, Hip circumference and weight measurement.;Energy and nutrient intake. Timepoint: beginning, second, fourth, sixth week and end of the intervention. Method of measurement: nutrient intake questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mehrangiz Ebrahimimamagani

Nutritional Research Center, Health and nutrition faculty, Tabriz University of Medical Sciences

ebrahimimamagani@tbzmed.ac.ir+98 41 1334 1113

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026