Comparison of mitomycin and dexametoson in Vernal Keratoconjunctivitis

Comparison of the efficacy of mitomycin c 0.01%versus dexamethason 0.1% in treatment of refractory in Vernal Keratoconjunctivitis keratoconjunctivitis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT201110097743N1

Enrollment

Registered

2012-02-29

Start date

2010-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vernal keratoconjunctivitis. vernal conjunctivitis

Interventions

Intervention 1: Intervention group :drop mytomicen 0/01% in duration 20 days,dievided 4,2qtt. Intervention 2: Control group:The patients will receive drop Dexamethazon phosphat 0/1% in duration 20 day

Treatment - Drugs

Intervention group :drop mytomicen 0/01% in duration 20 days,dievided 4,2qtt

Control group:The patients will receive drop Dexamethazon phosphat 0/1% in duration 20 days,divided 4,2qtt

Eligibility

Sex/Gender

All

Age

6 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria :the paitient with Refractory Vernal Keratoconjunctivitis. Exclusion criteria :croneal and conjunctivitis complication due to mitomycin c 0.01% efficacy of drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Symptom: photophobia, tearing, itching, discharg to four grad: non complication, mild, modrat (complication half of day), sever (complication whole day). Timepoint: Befor and after treatment (after 20 days). Method of measurement: Qestion.;Conjunectival injection whit 4 grade;no injection-mild-modrat-sever bolbar injection. Timepoint: Befor and after treatment (after 20 days). Method of measurement: Examination.;Upper lid conjunectival hyperthrophy with 4grade:no-mild -modrat and sever pupillary hyperthrophia. Timepoint: Befor and after treatment (after 20 days). Method of measurement: Examination.;Puncted keratitis with 4 grade :no-Puncted in 1/4 serface of cornoal-Puncted in 1/2 serface of cornoal-Puncted in >3/4 serface of cornoal. Timepoint: Befor and after treathmen(after 20 days)t. Method of measurement: Examination.	—

Measure

Time frame

Symptom: photophobia, tearing, itching, discharg to four grad: non complication, mild, modrat (complication half of day), sever (complication whole day). Timepoint: Befor and after treatment (after 20 days). Method of measurement: Qestion.;Conjunectival injection whit 4 grade;no injection-mild-modrat-sever bolbar injection. Timepoint: Befor and after treatment (after 20 days). Method of measurement: Examination.;Upper lid conjunectival hyperthrophy with 4grade:no-mild -modrat and sever pupillary hyperthrophia. Timepoint: Befor and after treatment (after 20 days). Method of measurement: Examination.;Puncted keratitis with 4 grade :no-Puncted in 1/4 serface of cornoal-Puncted in 1/2 serface of cornoal-Puncted in >3/4 serface of cornoal. Timepoint: Befor and after treathmen(after 20 days)t. Method of measurement: Examination.

—

Secondary

Measure	Time frame
Trantarsal dot with 4 grade:no-(1-2)dot-(3-4)dot->4dot. Timepoint: Befor and after treathment(after 20 days). Method of measurement: Examination.;Limbal edema with 4 grade:no-180 degree limbal area. Timepoint: Befor and after treathment(after 20 days). Method of measurement: Examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNooshin Bazzazi

Hamedan Univercity of Medical Sciences

n_bazzazi@yahoo.com ; bazzazi@umsha.ac.ir+98 81 1821 5151

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026