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Effect of infusion of propofol and dexmedetomidine on hemodynamic and sedation parameters

Comparison of the effect of infusion of propofol and dexmedetomidine on hemodynamic parameters and sedation in the recovery room in patients undergoing laparoscopic Cholecystectomy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20111009007745N12
Enrollment
64
Registered
2024-08-05
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of the effect of two drugs on hemodynamic changes and sedation in recovery.

Interventions

Intervention 1: Intervention group: Patients are divided into two groups. The first group: propofol from Tehran Shimi Pharmaceutical Company with a dose of 75-125 mcg/kg/hour until the end of the oper
It is injected until the end of the procedure.

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Candidate patients for elective laparoscopic cholecystectomy surgery under general anesthesia ASA class I No history of addiction No co-morbidities No use of benzodiazepines Consent to participate in the study Not being allergic to the study drugs Absence of pregnancy or breastfeeding

Exclusion criteria

Exclusion criteria: The need for simultaneous surgery Changing the surgical method to classic open cholecystectomy Recovery time more than forty-five minutes

Design outcomes

Primary

MeasureTime frame
Systolic pressure changes. Timepoint: Every 10 minutes from the start of the operation to discharge from recovery. Method of measurement: Use of sphygmomanometer.;Investigation of agitation in recovery. Timepoint: Every 10 minutes from the start of the operation to discharge from recovery. Method of measurement: Richmond Agitation-Sedation Scale.;Diastolic pressure changes. Timepoint: Every 10 minutes from the start of the operation to discharge from recovery. Method of measurement: Use of sphygmomanometer.;Investigation of sedation in recovery. Timepoint: Every 10 minutes from the start of the operation to discharge from recovery. Method of measurement: Richmond Agitation-Sedation Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Mansourian

Yasouj University of Medical Sciences

Afshin.mansourian@yahoo.com+98 74 3333 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026