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The effect of combine fentanyl and midazolam on pain management and prevention of chronic pain

The effect of Fentanyl and Midazolam on pain control and chronic pain prevention in patients with lower limb fracture

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20111009007745N10
Enrollment
100
Registered
2021-09-19
Start date
2021-09-06
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Control of pain and prevention of chronic pain in patients with lower limb fracture. Fracture of femur

Interventions

Intervention 1: Intervention group: Patients with lower limb fractures who are non-emergency candidates for surgery are selected. In the inpatient ward, informed consent is obtained to participate in

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 30-60 years old patients with isolated femoral fractures who are not candidated for emergency surgery

Exclusion criteria

Exclusion criteria: Patients with a history of diabetes, addiction, hypertension, or oral pain relief intake drugs, or history of chronic pain

Design outcomes

Primary

MeasureTime frame
Pain control and prevention of chronic pain in patients with lower limb fractures by Fentanyl Infusion and Midazolam. Timepoint: The effect of fentanyl and midazolam infusion on pain management and prevention of chronic pain in patients with lower extremity fracture The patient's pain is evaluated after five hours, 15 hours, 24 hours from the time of admission and starting the infusion drugs. In 24 hours after the operation, the same procedure is measured 5, 15, 24 hours after the operation. After discharge from the hospital, follow-up is done on monthly through with questionnaires mentioned, and all patients were monitored for 6 months. Method of measurement: Based on McGill's Modified Inventory and Visual Analog Scale.

Secondary

MeasureTime frame
Quality of life score. Timepoint: Quality of life scores are assessed 1, 3, and 6 months after discharge from the hospital. Method of measurement: Short questionnaire 12 health questions (SF12), designed by War, Kasinski, Keller.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Mansourian

Yasouj University of Medical Sciences

afshin.mansourian@yahoo.com+98 74 3322 4721

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026