Condition 1: Biliary Colic. Condition 2: stress response. Calculus of gallbladder without cholecystitis Abnormal finding of blood chemistry, unspecified
Conditions
Interventions
Intervention 1: Group 1 (standard intraabdominal pressure):
Laparoscopic cholecystectomy is performed using CO2 with standard intra-abdominal pressure of 14 mmHg. Intervention 2: Group 2 (Low intraabd
Treatment - Surgery
Group 1 (standard intraabdominal pressure):
Laparoscopic cholecystectomy is performed using CO2 with standard intra-abdominal pressure of 14 mmHg.
Group 2 (Low intraabdominal pressure):
Laparoscopic cholecystectomy is performed using CO2 with low intra-abdominal pressure of 8 mmHg.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) patients aged 18 years or older 2) with diagnosis of biliary colic and 3) ASA class I or II , who were 4) candidate for Laparoscopic cholecystectomy admitted in Shariati hospital, Tehran Exclusion criteria: 1) Cases of acute cholecystitis, 2) concurrent inflammatoary condition like acute pancreatitis, 3) uncured malignancy, 4) major intraoperative or postoperative complications and 5) severe systemic disease (ASA class three or greater)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood cortisol. Timepoint: preoperatively, 6 and 24 hours postoperatively. Method of measurement: laboratory based on mg/dl.;CRP. Timepoint: preoperatively, 6 and 24 hours postoperatively. Method of measurement: laboratory based on mg/l.;Blood glucose. Timepoint: preoperatively, 6 and 24 hours postoperatively. Method of measurement: laboratory based on mg/dl.;Blood adrenalin. Timepoint: preoperatively, 6 and 24 hours postoperatively. Method of measurement: laboratory based on pg/ml. | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine volume. Timepoint: during surgery. Method of measurement: urine bag based on cc.;Heart rate. Timepoint: at the beginning of surgery, every 15 minutes and at the end of the surgery. Method of measurement: monitoring equipment based on pulse rate per minute.;Length of surgery. Timepoint: after surgery. Method of measurement: watch based on minutes.;End tidal CO2. Timepoint: at the beginning of surgery, every 15 minutes and at the end of the surgery. Method of measurement: Capnography based on mmhg.;Mean arterial pressure. Timepoint: at the beginning of surgery, every 15 minutes and at the end of the surgery. Method of measurement: monitoring equipment based on mmhg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZhamak Khorgami
Tehran University of Medical Sciences - Shariati Hospital
Outcome results
None listed