Idiopathic urticaria. Idiopathic urticaria
Conditions
Interventions
Intervention 1: one tablet Atorvastatin (40mg/Kg) every 12 hours (twice daily) in patient group until 3 month. Intervention 2: one tablet placebo every 12 hours (twice daily) until 3month in control g
Treatment - Drugs
Placebo
one tablet Atorvastatin (40mg/Kg) every 12 hours (twice daily) in patient group until 3 month.
one tablet placebo every 12 hours (twice daily) until 3month in control group
Sponsors
Research Council of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: presence of utricaria more than 8 weeks, Normality of thyroids assay test, Negativity of antithyroglobulin, antimicrosomal antibodies and skin prick test for inhale and oral common allergens Exclusion criteria: Addiction, Systemic and chronic diseases, Pregnancy
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Utricaria severity. Timepoint: Baseline and at the end of treatment course. Method of measurement: Utricaria severity is calculated according to Breneman et al to 4 categories; Mild, Moderate and sever. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokines Variations. Timepoint: baseline and after the treatment course. Method of measurement: Measuring selective cytokines by Eliza method in lymphocyte culture. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Farahzad Jabbari
Allergy Research Center, Mashahd University of Medical Sciences
Outcome results
None listed