Renal colic. Calculus of kidney and ureter
Conditions
Interventions
Intervention 1: One group received morphine 0.1 mg/kg intravenous and ketamine (0.1 mg/kg/dose intravenous , maximum dose = 0.4 mg/kg),. Intervention 2: another group received Morphine ( 0.1 mg/kg i
Treatment - Drugs
One group received morphine 0.1 mg/kg intravenous and ketamine (0.1 mg/kg/dose intravenous , maximum dose = 0.4 mg/kg),
another group received Morphine ( 0.1 mg/kg intravenous ) and placebo
Sponsors
Tehran University of Medical Sciences-Deputy for research affairs
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Previous nephrolithiasis , age between 18 to 50 years old, severity of pain at least 6 from 10, systolic blood pressure >= 90 mmHg, heart rate = 60-120/m, respiratory rate = 8-22/m, o2sat >= 90%, no addiction to opiate or psychiatric drugs, no use analgesic drugs or opioid before recording the data, no history of chronic liver disease or kidney or respiratory disease, no history of coagulopathy or blood disorders or chronic psychiatric disorder, no use of psychiatric drugs. Exclusion criteria: The patient who is not interested in study, addiction to opiate or psychiatric drugs, allergy to morphine or ketamine, inability to perception of VAS
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of pain. Timepoint: Before prescription the medication, 10, 30, 60, 90 and 120 minutes after medication. Method of measurement: VAS ( visual analog scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea. Timepoint: Before prescription the medication, 10, 30, 60, 90 and 120 minutes after medication. Method of measurement: Questionnaire.;Agitation. Timepoint: Before prescription the medication, 10, 30, 60, 90 and 120 minutes after medication. Method of measurement: Questionnaire.;Diplopia. Timepoint: Before prescription the medication, 10, 30, 60, 90 and 120 minutes after medication. Method of measurement: Questionnaire.;Hallucination. Timepoint: Before prescription the medication, 10, 30, 60, 90 and 120 minutes after medication. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Bidi nader
Tehran University of Medical Sciences
Outcome results
None listed