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Effect of Aspirin in schizophrenia

Effect of Aspirin augmentation on cognitive & clinical symptoms of schizophrenic patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201109287660N1
Enrollment
40
Registered
2012-11-08
Start date
2012-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia. Paranoid schizophrenia

Interventions

Case group:Tab Aspirin 500 mg ,BID( Abidi company)
Intervention 1: Case group:Tab Aspirin 500 mg ,BID( Abidi company). Intervention 2: placebo group: tab placebo Aspirin like 500 mg ,BID.
Placebo
Treatment - Drugs
placebo group: tab placebo Aspirin like 500 mg ,BID

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1 - Is based on DSM-IV diagnosis of schizophrenia. 2 - The patient or patient's guardian consent to participate. 3 - PANSS score at the beginning of the project is more than 60. 4 - less than 5 years of disease duration and between 3 to 1 episodes. 5 - No physical disease based on clinical examination. 6 - Chronic NSAID is not used. 7 - Not taking corticosteroids. 8 - Not pregnant. 9 - there is no contraindication for aspirin and omeprazole. Exclusion criteria: 1 - Sensitivity to the drug 2 - Patients who choose to be excluded. 3 – Require other drugs. (Anticholinergics and benzodiazepines are excepted) 4 – Where ECT is needed.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cognitive disorders. Timepoint: baseline and 3th,6th,12th weeks. Method of measurement: cognition tests.;Clinical symptoms. Timepoint: baseline and 3th,6th,12th weeks. Method of measurement: PANSS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Tavakoli

Psychiatric Ibnesina Hospital

tavakolim881@mums.ac.ir+98 51 1761 1849

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026