Using antioxidants with oral contraceptives

Effect of vitamin E and C supplements on lipid peroxidation and GSH-dependent antioxidant enzymes status in the blood of women consuming oral contraceptives

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201109267641N1

Enrollment

120

Registered

2011-10-31

Start date

2011-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral contraceptive pill taking. Oral contraceptives

Interventions

Intervention 1: 150 mg of vitamin C and 200 IU vitamin E for 4 weeks. Intervention 2: no intervention.

Treatment - Drugs

150 mg of vitamin C and 200 IU vitamin E for 4 weeks

no intervention

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Iranian; age between 18-40; body mass index (BMI) 19-25; not using other supplement drugs and vitamin during the previous 3 months; not using cigarette and alcohol; not using special drugs; not having any known disease; using contraceptive pills for at least 1 and maximum 10 years; not having breast feeding. Excluding criteria: some special disease during study; changing the pregnancy prevention way during study; exit from study or immigration.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Lipid peroxidation. Timepoint: one time and 1 month after ocp taking. Method of measurement: photometery.	—

Secondary

Measure	Time frame
Antioxidant enzymes. Timepoint: one time 1 month after ocp taking. Method of measurement: photometery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fatemeh Zal

Shiraz university of medical sciences

zalf@sums.ac.irfatemehzal@yahoo.com+98 71 1230 3029

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026