The effect of single dose pregabaline in reducing postoperative pain following photo refractive keratectomy (PRK)

Comparative study in The effect of single dose pregabaline in reducing postoperative pain following photo refractive keratectomy (PRK)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201109231617N5

Enrollment

Registered

2012-05-21

Start date

2012-05-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Ocular pain

Interventions

Intervention 1: Pregabalin 50 mg oral tablet with a glass of water 30 minutes before surgery. Intervention 2: Placebo oral tablet with a glass of water 30 minutes before surgery.

Prevention

Pregabalin 50 mg oral tablet with a glass of water 30 minutes before surgery

Placebo oral tablet with a glass of water 30 minutes before surgery

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patient consent to perform PRK and consent to participate in the study. Exclusion criteria included corneal injuries and allergic to medicine and unwillingness to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 72 houres after dischurge. Method of measurement: Visual analogue score.	—

Secondary

Measure	Time frame
Analgesic use. Timepoint: 72 houres after dischurge. Method of measurement: Calculating dosage.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayebeh kazerooni

Imam Reza Hospital

mchoobsaz@kums.ac.ir+98 83 1724 6708

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026