Traumatic diffuse brain injury. Unspecified injury of head
Conditions
Interventions
Intervention 1: Treatment with Simvastatin 80 mg daily for 10 days with screen Alkp weekly for drug side effect , accumulation of patients information include: GCS at admission and days 3 ,10 and CT s
Treatment - Drugs
Placebo
Treatment with Simvastatin 80 mg daily for 10 days with screen Alkp weekly for drug side effect , accumulation of patients information include: GCS at admission and days 3 ,10 and CT scan finding incl
For Placebo use a neuter substance like Simvastatin prepare by pharmacy ward administered for 10 days , accumulation of patients information include: GCS at admission and days 3 ,10 and CT scan find
Sponsors
Vice chancellor for research, Ahvaz Jundishapour University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion: patients with GCS 8-12 Exclusion: patients with GCS less 8 and more 12
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glascow coma scale (GCS). Timepoint: Day 1,3,10. Method of measurement: According to GCS score table.;Glascow outcome scale (GOS). Timepoint: Mount 1,3,6. Method of measurement: According to GOS score table. | — |
Secondary
| Measure | Time frame |
|---|---|
| Myositis. Timepoint: Every week? alcalin phosphatase. Method of measurement: IU/L. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Rahbarian
Ahvaz Jundishapour University of Medical Sciences
Outcome results
None listed