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comparison the efficacy of bovine colostrum with topical triamcinolone acetonide 0/1%

Comparison the efficacy of bovine colostrum with topical triamcinolone acetonide 0/1% in the treatment of erosive oral lichen planus.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201109197594N1
Enrollment
40
Registered
2012-09-04
Start date
2012-10-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral lichen planus. Lichen planus

Interventions

Intervention 1: Intervention group: Five ml of pasteurized bovine colostrum under standard conditions between patients in the distribution of sterile vial and instructions for its use, both in writing
Treatment - Drugs
Intervention group: Five ml of pasteurized bovine colostrum under standard conditions between patients in the distribution of sterile vial and instructions for its use, both in writing and orally to
control group: This group of patients treated with triamcinolone acetonide is also called the drug four times daily for 4 weeks and the lesion can be localized.Meanwhile, 10 minutes after taking dru

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients with erosive oral lichen planus; lack of effective systemic drugs for at least three months of oral lichen planus and lack of effective topical medications for at least a month of oral lichen planus. Exclusion criteria: systemic disease; taking any medication lichenoied and consumption of any tobacco.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Clinical extent of the lesion. Timepoint: Before Intervention- after two weeks Intervention -after four weeks Intervention. Method of measurement: Ruler (per square millimeter).

Secondary

MeasureTime frame
Pain. Timepoint: Before Intervention- after two weeks Intervention -after four weeks Intervention. Method of measurement: According to statements made by the patient (by scale VAS).;Burning sensation. Timepoint: Before Intervention- after two weeks Intervention -after four weeks Intervention. Method of measurement: According to statements made by the patient (by scale VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Ebrahimpour

School of Dentistry, Tehran University of Medical Sciences

ali_e66110@yahoo.com+98 913 329 1873

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026