Comparison of General Anesthesia and Combined General Epidural Anesthesia regarding bleeding and post-operative pain

Comparison of General Anesthesia and Combined General Epidural Anesthesia regarding bleeding and post-operative pain after lumbar discectomy surgeries

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201109173773N5

Enrollment

Registered

2012-01-05

Start date

2010-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Lumbar post-operative pain. Condition 2: bleeding during lumbar operation. Fractures involving thorax with lower back and pelvis with limbs Hypotension, unspecified

Interventions

Intervention 1: Intervention group first receive epidural anesthesia in sitting position (by number 9 catheter and 10 cc Lidocaine 1% +10 cc Bupivacaine 0.5% + 1 cc Fentanil) then in supine position t

Treatment - Drugs

Placebo

Intervention group first receive epidural anesthesia in sitting position (by number 9 catheter and 10 cc Lidocaine 1% +10 cc Bupivacaine 0.5% + 1 cc Fentanil) then in supine position they will be anes

Control group will only be anesthetized generally. Introperative bleeding volume, hemodynamic condition = mean blood pressure, heart rate, and first post operative pain scale based on VAS & amount of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients undergoing discectomy operation for disc herniation at 1-2 levels. Exclusion criteria: A.S.A class more than 3, Multilevel spinal stenosis (more 2 level), coagulopathy, lumbar localized infection, lumbar region abnormalities, and patients who have contraindications for regional anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: during operation. Method of measurement: milliliter.;Pain. Timepoint: At 5, 10, 15, 20 minutes at recovery & 4, 10, 24 hour after operation at ward. Method of measurement: Visual Analogue Scale = VAS.	—

Secondary

Measure	Time frame
Blood Hb. Timepoint: afetr operation. Method of measurement: gr%.;Mean Blood Pressure. Timepoint: During operation. Method of measurement: Monitoring Devices.;Heart Rate. Timepoint: During operation. Method of measurement: Monitoring devices.;Morphine. Timepoint: During 1 day after operation. Method of measurement: Milligram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Khajavi M.D.

Tehran University of Medical Sciences

khajavim@tums.ac.ir+98 21 63120

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026