Comparison of Effects of Sublingual Misoprostol and Infusion Oxytocin in Reduction of Bleeding at Cesarean

Comparative of Effects of Sublingual Misoprostol and Infusion Oxytocin in Reduction of Bleeding at Cesarean

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201109104025N4

Enrollment

180

Registered

2011-12-12

Start date

2011-03-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child birth and priperium. O60-O75

Interventions

Intervention group:sublingual misoprostol 200micrograms Control groups:Infusion20 unit oxytocin,misoprostol 400 micrograms.

Treatment - Drugs

Intervention group:sublingual misoprostol 200micrograms Control groups:Infusion20 unit oxytocin,misoprostol 400 micrograms

Eligibility

Sex/Gender

Female

Age

15 Years to 44 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Elective or Emergency Cesarean Deliveries with Incision in Lower Segment of uterus, Gestational Age more than 37 Weeks Exclusion criteria:Anemia;Multiple pregnancy;Polyhydraminus;Prolonged labor;Premature rupture of membrane, History of diabetes mellitus,Hypertension,Cardiovascular disease,coagulopathy disorders, Placenta Previa & Placenta Abruption, Vaginal Bleeding.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intraoperative bleeding. Timepoint: At the time of surgery. Method of measurement: Measured with the blood suctioned in cc by the graded container.	—

Secondary

Measure	Time frame
Fever. Timepoint: During 48 hrs after surgery, measured every 3 hours. Method of measurement: Persist fever more than 38 ° c, with thermometer.;Change in basal pulse rate. Timepoint: Before surgery & intraoperative & 6 hrs after surgery. Method of measurement: Pulse rate in one minute.;Changing of blood pressure. Timepoint: Before surgery & intraoperative & 6 hrs after surgery. Method of measurement: Measuring with Sphygmomanometer.;Diarrhea. Timepoint: Before & 6 hrs after surgery. Method of measurement: question about change in frequency of defecation or its consistency (watery stool).;Vomiting. Timepoint: Before & 6 hrs after surgery. Method of measurement: Question about forceful expulsion of stomach contents.	—

Measure

Time frame

Fever. Timepoint: During 48 hrs after surgery, measured every 3 hours. Method of measurement: Persist fever more than 38 ° c, with thermometer.;Change in basal pulse rate. Timepoint: Before surgery & intraoperative & 6 hrs after surgery. Method of measurement: Pulse rate in one minute.;Changing of blood pressure. Timepoint: Before surgery & intraoperative & 6 hrs after surgery. Method of measurement: Measuring with Sphygmomanometer.;Diarrhea. Timepoint: Before & 6 hrs after surgery. Method of measurement: question about change in frequency of defecation or its consistency (watery stool).;Vomiting. Timepoint: Before & 6 hrs after surgery. Method of measurement: Question about forceful expulsion of stomach contents.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Soudabeh Eshghi ali

Kermanshah University of Medical Sciences (KUMS)

atusaeshghi@yahoo.com+98 912 580 8928

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026