Poly cystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Metformin was started after two months of CC to allow for the washout of the latter. All women were examined clinically and their weight, height and body mass index (BMI) recorded. All patients receiv
Treatment - Drugs
Sponsors
Semnan university of medical scienses
Eligibility
Sex/Gender
Female
Age
19 Years to 42 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: women who were 19-42 years of age with period of infertility more than 1.5 years; normal serum prolactin and thyroid function tests; having documented patent tubes by hysterosalpingography; no other infertility factor and failed to ovulate with a dose of CC of 150 mg/day for 5 days from day 3 of the period.The women were excluded from the study if they were diabetic; taking any medication that could influence carbohydrate metabolism; had hypertension or abnormal renal or liver function tests; and undergone ovarian drilling.Hirsutism was diagnosed when the Ferriman and Gallway score is >8 The diagnosis of PCOS was according to the Rotterdam Criteria.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation, Pregnancy and Cumulative pregnancy rates in different doses of letrozole. Timepoint: During and the end of treatment. Method of measurement: Sonography and BHCG. | — |
Secondary
| Measure | Time frame |
|---|---|
| The mean number of follicles= 18 mm, the mean of follicular size and endometrial thickness on the day of HCG administration. Timepoint: During treatment. Method of measurement: Sonograhy and BHCG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzam Azargoon
Semnan university of medical sciences
Outcome results
None listed