Comparing the effect of peritoneal infiltration and subcutaneous infiltration of Bupivacaine 0.5 % on postoperative pain in patients with acute Appendicitis

Comparing the effects of intraperitoneal and subcutaneous injection of Bupivacaine on postoperative pain of appendicitis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201109067491N1

Enrollment

126

Registered

2011-10-16

Start date

2010-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

appendicitis. Acute appendicitis

Interventions

Intervention 1: Group A: peritoneal infiltration of Bupivacaine 5% ( 1mg/kg). Intervention 2: Group B: subcutaneous infiltration of Bupivacaine 5% ( 1mg/kg). Intervention 3: Group C: without any injec

Treatment - Drugs

Group A: peritoneal infiltration of Bupivacaine 5% ( 1mg/kg)

Group B: subcutaneous infiltration of Bupivacaine 5% ( 1mg/kg)

Group C: without any injection

Eligibility

Sex/Gender

All

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age between 15-45 years; acute appendicitis. Exclusion criteria: addiction; complicated appendicitis (perforation, abscess, gangrene); patient with psychology disorders; diabetes and history of chronic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain after operaion. Timepoint: 6, 12 and 24 hours after operaion. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Pethedin dosage. Timepoint: 24 haur after operation. Method of measurement: number of adminstrated pethedin dosage.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Fazel

Kashan Univercity of Medical Sciences

Mdfazel@yahoo.com+98 36 1555 2999

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026