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The Effect of topical lipogel containing herbal extracts of Ziziphus jujuba and Echium amoenum on pruritus severity in hemodialysis patient

Trial comparison of the effect of cutaneous lipogels containing Jujube and Echium amoenum plant extracts with placebo on the severity of pruritus in hemodialysis patients.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110906007494N33
Enrollment
50
Registered
2020-09-15
Start date
2020-10-11
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pruritus in hemodialysis patients. Pruritus, unspecified

Interventions

Intervention 1: Intervention group: Due to the fact that the study is a cross-over method, there are 25 people in each group. A group of 25 people with jujube and Echium amoenum lipogel will be repla

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hemodialysis patients aged 18 years and older End-stage renal disease undergoing regular dialysis treatment at least two or three times a week for six months Having itching in the last two weeks and having an itching intensity score using the Usipovich Itching Intensity Scale (ISS) in the range of severe and moderate pruritus Full alertness and ability to communicate Parathyroid hormone (PTH), <300 Phosphor(P) <6

Exclusion criteria

Exclusion criteria: Existence of wounds in the limbs Generalized limb edema (more than one plus (+1) Pregnancy Breastfeeding Other chronic diseases and cancer Taking other topical medications and antihistamines History of any allergies (skin, especially to plant compounds)

Design outcomes

Primary

MeasureTime frame
Pruritus. Timepoint: The first visit; the first, second, third and fourth weeks after starting to use lipogels. Method of measurement: Itching 48-point scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Masoumeh Bagheri Nesami

Mazandaran University of Medical Sciences

az_faraji200@yahoo.com+98 11 3565 2616

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026