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Comparison of effects of Remifentanil and Fentanyl in blood pressure and heart rate changes due to tracheal intubation in preeclamptic pregnant women candidate for cesarean section

Comparison of effects of Remifentanil and Fentanyl in blood pressure and heart rate changes due to tracheal intubation in preeclamptic pregnant women candidate for cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201108294969N2
Enrollment
34
Registered
2011-09-22
Start date
2007-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia. Gestational [pregnancy-induced] hypertension with significant proteinuria

Interventions

Intervention 1: injection of 0.05 microgram/kg Remifentanil during 3 minutes before induction of anesthesia. Intervention 2: injection of 1 mg/kg Fentanyl 3 minutes before induction of anesthesia.
Prevention
injection of 0.05 microgram/kg Remifentanil during 3 minutes before induction of anesthesia
injection of 1 mg/kg Fentanyl 3 minutes before induction of anesthesia

Sponsors

Tehran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: pregnant women with preeclampcia, between 20 and 40 years old, candidate for elective or emergency cesarean section

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: before induction of anesthesia,before tracheal intubation,after tracheal intubation. Method of measurement: automatic.;Diastolic blood pressure. Timepoint: before induction of anesthesia,before tracheal intubation,after tracheal intubation. Method of measurement: automatic.;Heart rate. Timepoint: before induction of anesthesia,before tracheal intubation,after tracheal intubation. Method of measurement: puls oxymeter.

Secondary

MeasureTime frame
Apgar score of newborn. Timepoint: 1st and 5th minute after birth. Method of measurement: number 1 to 10 , depending on breathing, heart rate,skin color,.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026