Treatment of preterm labor

A comparison between nitroglycerin skin patch and nifedipin for the treatment of preterm labbor

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201108262624N8

Enrollment

120

Registered

2012-06-05

Start date

2011-04-03

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labor. Onset (spontaneous) of labour before 37 completed weeks of gestation

Interventions

Intervention 1: Nifedipin prescription. Intervention 2: TNG skin patch prescription.

Treatment - Drugs

Nifedipin prescription

TNG skin patch prescription

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: All women who had 4 uterine contractions in 20 minutes or cervical dilatation = 1 cm and effacement = 80% with a gestational age of 26 to 36 weeks were entered the study. Exclusion criteria were: PROM; any maternal or fetal indications for pregnancy termination; IUFD; dilatation of more than 5 cm; allergy to TNG and tocolytic use during previous 24 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Preterm labor. Timepoint: 48 hours and 7 days. Method of measurement: delivery.	—

Secondary

Measure	Time frame
Adverse effects of drugs. Timepoint: every 15 minutes for 1 hour then every 4 hours. Method of measurement: blood pressure measurement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Kashanian

Tehran University of Medical Sciences

maryamkashanian@yahoo.com+98 21 7752 3487

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026