Effect of Phenytoin cream on episiotomy wound healing and relif pain

The comparison of the effectiveness of phenytoin cream with povidone iodine solution on episiotomy healing and pain relief in primipara women refering to allzahra medical educatinal hospital in Tabriz 2010.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201108243027N9

Enrollment

120

Registered

2011-10-09

Start date

2010-09-07

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perineal wound care. Disruption of perineal obstetric wound

Interventions

Intervention 1: Intervention group 1: phenytoin cream + placebo solution. Intervention 2: Intervention group2: povidon iodine solution + placebo cream.

Treatment - Drugs

Intervention group 1: phenytoin cream + placebo solution

Intervention group2: povidon iodine solution + placebo cream

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Full term pregnancy; being nulliparous; no special diet;age 18-35 years; no specific diseases (cardiovascular, hepatic, renal; diabetes; coagulopathy diseases;anemia, no history of skin diseases; persistent constipation and hemorroids); mul-nutrition;not taking specific drugs ( such as anticoagulant;anti depressants;anti epileptic;antibiotics;immuno-suppressive drugs); no smoking and alcohol and drugs; having literacy; non- obese (BMI<29; according to the same scale);anterior fetal presentation;Episiotomy on gynecological bed;Episiotomy repair by chromic catgut sutures after prep and drep using the same techniques and in less than 30 minutes;visible injury or previous surgery in the perineal region;normal pregnancy;subjects' willingness to participate in the study; Exclusion criteria: Hematomas or infection after the delivery; history of perineal and vaginal surgery;mismatch between maternal pelvis and fetal size (based on pelvis examination);disorders in labor (first stage of labor after 14 h;the second stage more than 2 h); prolonged rupture of amniotic sac (more than 18 h); manual placenta removal;manipulation of the perineum; excessive bleeding after childbirth; need for neonated resuscitation; extended Episiotomy;use of delivery aids;non- persistent use of drugs; women who decide to withdraw from the research.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Episiotomy wound healing. Timepoint: 24 hours and 10 days after delivery. Method of measurement: REED SCALE (Redness, echimosses, edema discharge, aproximation).	—

Secondary

Measure	Time frame
Episiotomy pain relief. Timepoint: 24 hours and 10 days after intervention. Method of measurement: VAS scale(vissual analog scale).	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026