Dyspepsia. dyspepsia
Conditions
Interventions
Intervention 1: Control group: Amoxicillin 1000mg twice daily, clarithromycin 500 mg twice daily,omeprazole 20 mg twice daily plus 600mg single dose of NAC for two weeks. Intervention 2: Intervention
Treatment - Drugs
Control group: Amoxicillin 1000mg twice daily, clarithromycin 500 mg twice daily,omeprazole 20 mg twice daily plus 600mg single dose of NAC for two weeks.
Intervention group: amoxicillin 1000 mg twice daily, clarithromycin 500 mg twice daily,omeprazole 20 mg twice daily for two weeks.
Sponsors
Vice – Chancellery of Research & Technology Affairs, Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: having the indications of endoscopy, i.e. age over 50 years with symptoms of dyspepsia, individuals with less than 50 years of age who are resistant to a 4-week treatment with gastric acid inhibitors Exclusion criteria: not willing to undergo endoscopy; having a history of taking antibiotics, bismuth, or proton pump inhibitors in the two weeks prior to the visit; suffering from severe diseases such as renal failure, heart or liver disease, chronic use of anti-inflammatory medications (either non steroidal or corticosteroids), history of surgery or known cases of extra- intestinal cancer, pregnancy, breast feeding
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H.pylori eradication rate. Timepoint: 4 weeks. Method of measurement: Urease breath test and histology. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: 4 weeks. Method of measurement: Checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Asghar Keshavarz
Emam reza hospital, Kermanshah University of Medical Sciences
Outcome results
None listed