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Effect of Dexametasone in ovarian response in PCOs women in IVF

Evaluation of Dexametasone supplementation for ovarian response in infertile women with polycystic ovaries in IVF-ICSI cycle

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201108174306N4
Enrollment
100
Registered
2011-10-09
Start date
2011-12-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Polycystic ovarian. Condition 2: Infertility. Polycystic ovarian syndrome Female infertility associated with anovulation

Interventions

Intervention 1: Adding 2 tab dexamethasone 5mg to ICSI routine protocol. Intervention 2: Routin Protocol of ICSI.
Treatment - Drugs
Adding 2 tab dexamethasone 5mg to ICSI routine protocol
Routin Protocol of ICSI

Sponsors

Vice chancellor of Technology and Research, Babol University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: infertile PCOS women candidate for the first cycle of ICSI, 20-35 yrs with infertility duration <5yrs. All patients with uterus abnormalities like myoma, intra uterine septum , women with endometriuma, allergy background to dexamethasone and hyperstimulation syndrome (OHSS) is excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Rate of dominant follicle. Timepoint: 12-16 days after ovulation day. Method of measurement: Number.

Secondary

MeasureTime frame
Rate of retrieved oocytes. Timepoint: 12-16 days after mensturation. Method of measurement: Number.;Fertilization rate. Timepoint: 16-18 days after mensturation. Method of measurement: number.;Abortion rate. Timepoint: 25-30 days after embryo transfer. Method of measurement: number.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Zahra Basirat

Babol University of Medical Sciences

zahra_basirat@yahoo.com; m.golsorkhtabar@gmail.com+98 11 1227 4882

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026