The effect of a gluten free diet and a diet which contain gluten on the treatment of IBS

Comparison between gluten-free regime and regime with gluten in symptoms of patients with IBS

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110816007350N2

Enrollment

140

Registered

2019-04-30

Start date

2014-06-22

Completion date

Unknown

Last updated

2019-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable bowel syndrome. Irritable bowel syndrome with diarrhea

Interventions

Intervention 1: Intervention group: In order to use the gluten free diet, the intervention group received a list of gluten free foods along with addressees of the stores which sell and distribute thes

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients with IBS referring to Gastroenterology Clinic of Imam Khomeini Hospital

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding The history of abdominal surgery Patients with opioid use Non-steroidal anti-inflammatory Long-term antibiotic drug consumption Kidney Failure The presence of serious physical illnesses Celiac disease Diabetes Organogenesis of the digestive system based on doing endoscopy and colonoscopy test Fail to adherence to gluten-free diet during patient studies

Design outcomes

Primary

Measure	Time frame
Abdominal pain. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Gas bowel. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Reduce the frequency of defecation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Increase the frequency of defecation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Diarrhea. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Constipation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.	—

Measure

Time frame

Abdominal pain. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Gas bowel. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Reduce the frequency of defecation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Increase the frequency of defecation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Diarrhea. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.;Constipation. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.

—

Secondary

Measure	Time frame
Incomplete evacuation of stools. Timepoint: Patients were first assessed by Rome 3 questionnaire and weeks after the end of the treatment period based period based on symptoms they were graded from 0-3. Method of measurement: Likert scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSina Babazadeh

Ahvaz University of Medical Sciences

babazadeh.s@ajums.ac.ir+98 31 3266 8337

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026