Isosorbide dinitrate effect on cervical ripening. Disorders related to long gestation and high birth weight
Conditions
Interventions
Intervention 1: Samples of investigation are divided into three groups based on randomly numbers table., in one group isosorbide dinitrate 40 mg should be placed vaginaly in posterior fornix.The Bis
Treatment - Drugs
Samples of investigation are divided into three groups based on randomly numbers table., in one group isosorbide dinitrate 40 mg should be placed vaginaly in posterior fornix.The Bishop score is det
Samples of investigation are divided into three groups based on randomly numbers table., in one group isosorbide dinitrate20 mg should be given oraly.The Bishop score is determined at the beginning of
Samples of investigation are divided into three groups based on randomly numbers tablethat one group is control.they dont take any drug.The Bishop score is determined at the beginning of the study.THE
Sponsors
Vice chancellor for research of Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
10 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1)Nulliparity 2)Gestational age>42 weeks 3)Bishop score<5 4)Singleton pregnancy 5)Cephalic presentation 6) filled Consent form. Exclusion criteria: 1)Premature rupture of membrane 2)Vaginal bleeding 3)Contraindication for ISDN 4)History of any uterian scar 5)Intolerance to ISDN 6)Any systemic disease 7)Laber pain 8)Oligohydramnios 9)IUGR 10)Non-reassuring FHR
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Time from full dilatation to delivery. Timepoint: Stage 2 of labor. Method of measurement: Minut.;Time from active phase to full dilation. Timepoint: Stage 1 of labor. Method of measurement: Minut.;From induction to active phase. Timepoint: active phase. Method of measurement: minut. | — |
Primary
| Measure | Time frame |
|---|---|
| Cervical ripening. Timepoint: 24 hours. Method of measurement: Vaginal exam. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Ladan Haghighi
Tehran University of Medical Sciences
Outcome results
None listed