Maxillofacial operations: trauma-orthognathic surgery. Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
Conditions
Interventions
Intervention 1: Patients in group Ob will receive a single dose of ondansetrone (0.15 mg/kg) 30 minutes before surgery. Intervention 2: Patients in group Oa will receive a single dose of ondansetrone
Treatment - Drugs
Patients in group Ob will receive a single dose of ondansetrone (0.15 mg/kg) 30 minutes before surgery
Patients in group Oa will receive a single dose of ondansetrone (0.15 mg/kg) 30 minutes before the end of surgery
Patients in group Mb will receive a single dose of metochlopramide (0.5 mg/kg) 30 minutes before surgery.
Patients in group Ma will receive a single dose of metochlopramide (0. 5 mg/kg) 30 minutes before the end of surgery.
Patients in group C (control group) will not receive any prophylaxis and drugs before surgery or at the end of surgery and metochlopramide will be used PRN after surgery
Sponsors
Vice Chancellor for Research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients candidate for maxillofacial surgery; 18-50 years of age; Patients undergoing IMF. Exclusion criteria: systemic diseases affecting nausea and vomiting; brain trauma in traumatic patients, as a factor influencing nausea and vomiting; clinical conditions indicating presence of factors for being placed in a high risk group; duration of surgery more than 3 hours; use of nausea- and vomiting-inducing drugs such as opiates.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: Recorded by inspection of nausea and asking after recovery.;Vomiting. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: recorded by inspection of vomiting. | — |
Secondary
| Measure | Time frame |
|---|---|
| Vertigo. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: Inspection and asking from the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Hossein Dabbagh Asadolahi Pour
Tabriz university of medical sciences, Imam Reza hospital
Outcome results
None listed