Acute Migraine Headache. Migraine
Conditions
Interventions
Intervention 1: Intervention group 1: To control headaches in this group ketorolac (C15H13NO3), a non-steroidal anti-inflammatory drug , will be administered through an intravenous (IV) infusion of 3
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-65 with a history of at least one year of migraine headache (with or without aura) with a history of 1 to 6 headache attacks of moderate to severe intensity per month in the 2 months prior to screening.
Exclusion criteria
Exclusion criteria: Patients with a history of congenital heart diseases. People with cardiovascular (such as angina and other atherosclerotic diseases) and/or lung diseases. Patients with cardiac arrhythmias even while under treatment. Patients suffering from cerebrovascular diseases (stroke, TIA and epilepsy). Patients suffering from ischemic bowel disease. people having renal or hepatic failure. Patients who have a history of alcohol or other substance abuse one year prior to the study. Presence of any symptoms suggesting neurological defects and/or other neurological pathologies. women who, are pregnant and/or breastfeed. patients who use OCPs. Patients who have asthma. People with a known allergy to Sumatriptan and/or non-steroidal anti-inflammatory drugs. Patients suffering from coagulopathies. Patients having a history of basilar migraines and/or of hemiplegic migraines. patients suffering from cluster headaches. Patients who have a previous association with health care system, or are currently working as a health care provider (due to disturbing the blinding process.) patients with an uncontrolled blood pressure (160 or more systole, distal 95 or more). patients who smoke.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Satisfaction with headache control. Timepoint: hourly. Method of measurement: questionnaire.;Satisfaction with the control of accompanying symptoms. Timepoint: hourly. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Headache control. Timepoint: hourly. Method of measurement: Visual Analog pain scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamad Shams Vahdati
Tabriz University of Medical Sciences
Outcome results
None listed