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The effects of epidural injection of glucocorticoid and glucocorticoid combined with bupivacaine in palliating chronic low back pain due to discopathy

The effects of epidural injection of glucocorticoid and glucocorticoid combined with bupivacaine in palliating chronic low back pain due to discopathy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201108137313N1
Enrollment
40
Registered
2011-11-07
Start date
2011-12-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic low back pain. Nerve root and plexus compressions in intervertebral disc disorders

Interventions

Intervention 1: methyl prednisolone, 80 mg via epidural injection. Intervention 2: methyl prednisolon, 80 mg, as well as bupivacaine 20 mg, injected via epidural route in one syringe.
Treatment - Drugs
methyl prednisolone, 80 mg via epidural injection
methyl prednisolon, 80 mg, as well as bupivacaine 20 mg, injected via epidural route in one syringe

Sponsors

vice-chancellor for Research, Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Chronic backache due to pure discogenic pain, signs of disk degeneration or herniation in MRI in the range of bulging to protrusion without motor and DTR involvement, Induction for epidural injection of glucocorticoid Exclusion criteria: Chronic backache less than 3 months, Previous surgery or the spinal column, Signs and symptoms of cauda equine, canal stenosis and psychosomatic disorders, drug addiction, receiving any medical treatment

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: 1 week, 2 weeks, 1 month to three months and 6 months. Method of measurement: pain free, mild, moderate, severe.;Straight leg rising test. Timepoint: 1 week, 2 weeks, 1 month to three months and 6 months. Method of measurement: Posetive (less than 60 degrees) and negative (more than 60 degrees) and also clinical examination variables.

Secondary

MeasureTime frame
Return to normal activities, social and economic. Timepoint: 1 week, 2 weeks, 1 month to three months and 6 months. Method of measurement: The question from patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Janmardi

Tabriz University of Medical Sciences

Reza_janmardi@yahoo.cm+98 41 1286 8237

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026