Gingival Graft

Culture of human gingival fibroblasts on an autologous scaffold and evaluation of its effect on augmentation of attached gingiva in comparison with the periosteal fenestration technique in patients with inadequate attached gingiva in a pilot clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201108135305N2

Enrollment

Registered

2013-10-14

Start date

2009-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gingival disease. Other and unspecified infectious diseases

Interventions

Intervention 1: In interventional side, gingival graft ( Platelet rich plasma + fibroblasts). Intervention 2: In control side, periosteal fenestration technique.

Treatment - Surgery

Treatment - Drugs

In interventional side, gingival graft ( Platelet rich plasma + fibroblasts)

In control side, periosteal fenestration technique

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: no systemic diseases that contraindicated periodontal surgery ; no medications affecting periodontal surgery ; no pregnancy or lactation ; no periodontal diseases ; no smoking ; full mouth plaque score and full mouth bleeding score 20% at the time of the surgical procedures

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Keratinized gingival width. Timepoint: baseline and after 3 months. Method of measurement: the distance between gingival margin and MGJ , measurment with periodontal probe.;Attached gingival width. Timepoint: baseline and 3 months later. Method of measurement: the distance between MGJ to base of the sulcus, measurment with periodontal probe.;Probing depth. Timepoint: baseline an 3 months later. Method of measurement: the amount of penetration of periodontal probe into the sulcus.	—

Measure

Time frame

Keratinized gingival width. Timepoint: baseline and after 3 months. Method of measurement: the distance between gingival margin and MGJ , measurment with periodontal probe.;Attached gingival width. Timepoint: baseline and 3 months later. Method of measurement: the distance between MGJ to base of the sulcus, measurment with periodontal probe.;Probing depth. Timepoint: baseline an 3 months later. Method of measurement: the amount of penetration of periodontal probe into the sulcus.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Mohammadi

Periodontics Department, Kerman Dental School

mmohammadi28@yahoo.com ; m_mohammadi@kmu.ac.ir+98 34 1211 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026