polyneuropathy and myopathy. Diabetic polyneuropathy
Conditions
Interventions
Intervention 1: In this study,during one year and a half,30 of patients admitted to the pediatric intensive care unit of Tabriz Children's Hospital and are more than one week under mechanical ventilat
In first group with 15 patients,in which the intervention is done, insulin is used in order to keep blood sugar in range of 140-180 milligram per decilitre (until the patient is connected to the venti
Treatment - Drugs
In this study,during one year and a half,30 of patients admitted to the pediatric intensive care unit of Tabriz Children's Hospital and are more than one week under mechanical ventilation and in the c
In second group with 15 patients which is called control group,distilled water as placebo will be used.Appropriate protocol in using distilled water,like insulin injection in intervened group,is conti
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria and who are under investigation in this study are the following: In this study,during one year and a half,30 of patients admitted to the pediatric intensive care unit of Tabriz Children's Hospital and are more than one week under mechanical ventilation and in the course of their hospitalization experience hyperglycemia (more than 180 milligram per decilitre) are divided into two groups; In first group with 15 patient insulin is used in order to keep blood sugar in range of 140-180 milligram per decilitre (until the patient is connected to the ventilator); In second group with 15 patient,distilled water as placebo will be used (Note that injection will be done by a person who has no information about the polyneuropathy and myopathy). Confounding variables are important in this study and the following people are excluded from study; spinal cord injuries; patients with Guillain Barre Syndrome; myasthenia gravis; patients with central nervous system problems or neuromuscular disease causing muscle weakness and paralysis before or during the hospitalization; hypophosphatemia. Appropriate methods to control confounding variables are according to observation,periods of physical examination,laboratory results such as blood and cerebro spinal fluid tests and EMG and NCV. It should be noted that the removal of these patients are so that in each point of the study (before the start of or during the study) if each of 5 problems above found by methods such as Electromygraphy and testing of cerebrospinal fluid or physical examination period,the patient will be excluded.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood glucose. Timepoint: Serial monitoring of blood glucose per hour (the aim of maintaining blood glucose range 140-180 milligram per decilitre). Method of measurement: Glucometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Polyneuropathy and myopathy. Timepoint: After extubation. Method of measurement: Electromyography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahram Sadegvand
Tabriz University of Medical Sciences
Outcome results
None listed