Comparing the effects of aerobic exercises and low-calorie diet on insulin resistance

Comparing the effects of aerobic exercises and low-calorie diet on inflammation and insulin resistance, a randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110811007297N6

Enrollment

Registered

2020-01-17

Start date

2019-05-05

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

People with overweight and obesity. Overweight and obesity

Interventions

Intervention 1: First intervention group: special diet that provides 500 calories less than the TEE (including 50-50% carbohydrate, 15-20% protein and 30-25% fat), totally 3500 per week. Intervention

Eligibility

Sex/Gender

Male

Age

35 Years to 50 Years

Inclusion criteria

Inclusion criteria: no constant physical activity BMI above 25

Exclusion criteria

Exclusion criteria: those with metabolic problems and diseases including thyroid disease, cancer, lipid profile problems, blood sugar, blood pressure, liver and kidney diseases those who used any special diet or had changed their diet over the past six months

Design outcomes

Primary

Measure	Time frame
Leptin, adiponectin, Chemerin, FBS, fasting insulin, insulin resistance index (HOMA-IR), hs CRP inflammatory index, interleukin 1ß, and interleukin-6. Timepoint: Before the intervention and 12 weeks later. Method of measurement: Blood sample.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Homayounfar

Fasa University of Medical Sciences

r_homayounfar@yahoo.com+98 21 8670 5503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026