Leiomyoma. A benign smooth muscle neoplasm arising from the body of the uterus. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.Uterine fibroids are the most common non-cancerous tumors in w
Conditions
Interventions
Intervention 1: First Intervention group: In the segmental electroacupuncture group, after inserting the needles in their predefined acupoints (two points located on the abdominal myotomes with common
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Non virgin females aged 18 until menopause Females who have uterine fibroids type 1-6 according to contemporary medicine standards Signing the informed consent form No need for immediate or emergency surgery intervention Being able to come to acupuncture clinic twice a week for 8 weeks Not suffering from adenomyosis or other genitourinary malignancies Non pregnant and not breastfeeding Not consuming hormonal drugs and drugs which can affect results of this study since 3 months ago Not suffering from severe heart / hepatic / renal failure No history of epilepsy Not participating in other acupuncture based studies Non smokers, not consuming alcohol Not suffering from uncontrolled diabetes and Hypertension Not having Hb bellow 10 mg/dl
Exclusion criteria
Exclusion criteria: Mismatching with the inclusion criteria after the start of the intervention (such as the need to take hormonal drugs or emergency surgery) Getting adenomyosis, genitourinary malignancies, severe heart/ hepatic/ renal failure and seizure during the study Not willing to get acupuncture for any reason Being absent from more than two consecutive treatment sessions Getting pregnant during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on mass size of dominant uterine fibroids before, immediately after intervention and in a 2 month follow-up. Timepoint: Before, immediately after intervention, 2 month after intervention. Method of measurement: Transvaginal doppler ultrasound.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on resistance index of uterine arteries before, immediately after intervention and in a 2 month follow-up. Timepoint: Before, immediately after intervention, 2 month after intervention. Method of measurement: Transvaginal doppler ultrasound.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on pulsatility index of uterine arteries before, immediately after intervention and in a 2 month follow-up. Timepoint: Before, immediately after intervention, 2 month after intervention. Method of measurement: Transvaginal doppler ultrasound.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on diameter of uterine arteries before, immediately after intervention and in a 2 month follow-up. Timepoint: Before, immediately after intervention, 2 month after intervention. Method of measurement: Transvaginal doppler ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on intensity and regularity of menstrual bleeding in patients with uterine fibroids before, immediately after intervention and in in a 2 month follow-up. Timepoint: before, immediately after intervention and in in a 2 month follow-up. Method of measurement: UFS-QOL questionnaire.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on pelvic tightness or pressure in patients with uterine fibroids before, immediately after intervention and in in a 2 month follow-up. Timepoint: before, immediately after intervention and in in a 2 month follow-up. Method of measurement: UFS-QOL questionnaire.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on frequent urination during daytime in patients with uterine fibroids before, immediately after intervention and in in a 2 month follow-up. Timepoint: before, immediately after intervention and in in a 2 month follow-up. Method of measurement: UFS-QOL questionnaire.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on frequent nighttime urination in patients with uterine fibroids before, immediately after intervention and in in a 2 month follow-up. Timepoint: before, immediately after intervention and in in a 2 month follow-up. Method of measurement: UFS-QOL questionnaire.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Acupuncture on feeling fatigued in patients with uterine fibroids before, immediately after intervention and in in a 2 month follow-up. Timepoint: before, immediately after intervention and in in a 2 month follow-up. Method of measurement: UFS-QOL questionnaire.;Evaluation and comparison of the effects of Segmental Electroacupuncture, Manual Acupuncture and Sham Ac | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Hooshyarazar
Mashhad University of Medical Sciences
Outcome results
None listed