Obesity. Obesity due to excess calories
Conditions
Interventions
Intervention 1: Intervention group: diet + exercise + Hypericum perforatum 750 mg QID for 6 weeks (made by School of Iranian and Complementary Medicine, Mashhad). Intervention 2: Control group: diet +
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: BMI 24.9 to 39.9 Women 18 years to premenopausal and men 18 to 60 years old Consent to participate in the study History of at least one monotherapy failure
Exclusion criteria
Exclusion criteria: Hypothyroidism, Cushing's syndrome, cancer, liver or kidney failure Psychiatric disorders associated with eating like anorexia nervosa and hyperorexia Using drugs effective on weight and metabolism in the previous month Using drugs that interfere with Hypericum perforatum such as protease inhibitors, amiodarone, anticoagulants, cyclophosphamide, cyclosporine, monoamine oxidase inhibitors, phenytoin, tacrolimus, tamoxifen and trazodone drug Drug abuser or alcoholism Breast-feeding, pregnancy or planning a pregnancy during the next two months Pacemaker and any metal device inside the body due to the use of Bioelectrical Impedance Analyzer Disability to do recommended physical activity Allergy to hypericum perforatum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appetite. Timepoint: Before intervention, week 3, week 6. Method of measurement: Visual Analogue Scale.;Body weight. Timepoint: Before intervention, week 3, week 6. Method of measurement: Kilogram.;Waist to hip ratio. Timepoint: Before intervention, week 3, week 6. Method of measurement: Centimeter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin. Timepoint: Before intervention, after intervention. Method of measurement: IU.;Fasting Blood Sugar. Timepoint: Before intervention, after intervention. Method of measurement: Mg/dl. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHoda Azizi
Mashhad University of Medical Sciences
Outcome results
None listed