Menopause. Menopausal and female climacteric states
Conditions
Interventions
Intervention 1: Intervention group: nettle in the form of Urtidin tablet 150 mg, 3 times/ day for 7 weeks. Intervention 2: Control group: nettle placebo tablet, three times a day for seven weeks.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: Post-menopausal women (defined as: amenorrhea for 12 months or more) who suffer from hot flashes. Age 45-60 years old Approval for treatment of hot flashes and consent to participate in the plan.
Exclusion criteria
Exclusion criteria: History of hysterectomy or oophorectomy Anticancer therapies due to malignancy History of estrogen-dependent cancers over the past five years History of allergy to urticaria History of known psychiatric disorders Hyperthyroidism or hypothyroidism Conditions and physical illnesses that are not suitable for this study: Cardiovascular disease (coronary artery disease, cerebrovascular disease and thromboembolic disorders) uncontrolled Hypertension or diabetes, kidney or liver failure use of anticoagulants Taking any medication for hot flashes such as HRT and SSRI in the past eight weeks Endometrial thickness over 12 mm in uterine ultrasonography Vaginal bleeding with unknown origin in the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of FSH, estradiol, LH. Timepoint: Before the study and at week 8. Method of measurement: blood test.;Severity of menopausal symptoms. Timepoint: Before the intervention, week 4 and 7. Method of measurement: Menopausal Rating Scale questionnaire.;Number and severity of hot flashes per day. Timepoint: One week before the study and at weeks 5 and 8. Method of measurement: Patient Daily Report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hoda Azizi
Mashhad University of Medical Sciences
Outcome results
None listed