very low birth weight neonates. Disorders related to short gestation and low birth weight, not elsewhere classified
Conditions
Interventions
Intervention 1: Intervention group: 100 mg/kg clofibrate orally in one dose. Intervention 2: Control group: distilled water as volume as intervention drug orally one dose.
Prevention
Intervention group: 100 mg/kg clofibrate orally in one dose
Control group: distilled water as volume as intervention drug orally one dose
Sponsors
Vice-chancellor for Research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
2 Years to 10 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: neonates with birth weight less than 1500 grams receiving intravenous lipid (IVL) for parental nutrition Exclusion criteria: presence of any Congenital anomaly, hemolytic disease (Rh or ABO incompatibility OR a positive Coombs’ test), hyperbilirubenemia, Infection (congenital or acquired), dehydration, G6PD deficiency, history of Phenobarbital intake either by Mother or infant
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum cholesterol. Timepoint: before intervention and one day after intervention. Method of measurement: measurement of serum cholesterol.;Serum triglyceride. Timepoint: before intervention and one day after intervention. Method of measurement: measurement of serum triglyceride. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ashraf mohammadzadeh
Neonatal Research Center
Outcome results
None listed