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Evaluation the effect of the Lornoxicam on the post-operative endodontic pain

Evaluation the effect of intraligamentry injection of the Lornoxicam on the post-operative endodontic pain in tooth with symptomatic irreversible pulpitis (Clinical Trial Study)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201108017191N1
Enrollment
40
Registered
2011-10-09
Start date
2011-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative endodontic pain. Other specified disorders of teeth and supporting structures

Interventions

Intervention 1: Interventional group: After inferior Alveolar injection and before the beginning of the treatment the primary group will receive an injection of 0.4 mL ( 0.2 mL in mesio buccal and 0.2
Treatment - Drugs
Interventional group: After inferior Alveolar injection and before the beginning of the treatment the primary group will receive an injection of 0.4 mL ( 0.2 mL in mesio buccal and 0.2 mL in disto buc
Control group: wil be injected with 0.4 mL of 2% Lidocain with EP 1/180000

Sponsors

Dental Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: healthy (ASA I, II); Patients with first or second mandibular molars who need endodontic treatment; Vital tooth without a history of past endodontic treatment; Patients with clinical evidence of irreversible Pulpits with moderate to severe pain; Patients without pre apical lesion and periodontal ligament enlargement more than 0.75-1mm on the x-ray images; Patients in the age group of 18-65 years old. Exclusion criteria: Pregnant or nursing; necrotic tooth; Patients with allergy or contraindication toward non-opioid or opioid painkillers such as aspirin or NSAIDs; People who have a history of acute peptic ulcer, during the past 12 months; People who have bleeding problems or have been taking anticoagulant drugs over the past month; Patients who have taken opioid or non opioid or steroid pain killers, antidepressants or sedative drugs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Post oprative endodontic pain. Timepoint: 6-12-24-48 hours after treatment. Method of measurement: Visual Analogue Scale (VAS 0-9mm).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Peyman Mehrvarzfar

Endodontic department, Dental School of Tehran Azad University

mani_tari@yahoo.com , mehrvarzfar@gmail.com , dr.p.mehrvarzfar@dentaliau.ir+98 912 104 5805

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026